Biography

    Sharon Sagiv is trained as an epidemiologist with research interests focused primarily on prenatal and early life exposure to environmental contaminants and neurodevelopment. She has investigated the effect of prenatal exposure to persistent organic pollutants, including PCBs and DDT, on birth outcomes and on neurodevelopment in young children. Current research activities include studying the effect of exposure to heavy metals, including lead, methylmercury and manganese, on behavioral outcomes in infants and school-aged children. She is also investigating associations of prenatal and postnatal exposure to polyfluoroalkyl chemicals (PFCs) with child growth and development, focusing on prenatal maternal and newborn thyroid function, somatic growth, metabolic function and neurodevelopment. Dr. Sagiv is also interested in the effects of environmental exposures on aging and neurocognitive decline.

Publications
    1. Sagiv SK, Thurston SW, Bellinger DC, Amarasiriwardena C, Korrick SA. Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/hyperactivity disorder-related behavior in children. Arch Pediatr Adolesc Med. 2012 Dec 1; 166(12):1123-31.
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    2. Ertel KA, Kleinman K, van Rossem L, Sagiv S, Tiemeier H, Hofman A, Jaddoe VW, Raat H. Maternal perinatal depression is not independently associated with child body mass index in the Generation R Study: methods and missing data matter. J Clin Epidemiol. 2012 Dec; 65(12):1300-9.
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    3. Sagiv SK, Thurston SW, Bellinger DC, Altshul LM, Korrick SA. Neuropsychological Measures of Attention and Impulse Control among 8-Year-Old Children Exposed Prenatally to Organochlorines. Environ Health Perspect. 2012 Feb 22.
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    4. Sagiv SK, Epstein JN, Bellinger DC, Korrick SA. Pre- and Postnatal Risk Factors for ADHD in a Nonclinical Pediatric Population. J Atten Disord. 2012 Jan 31.
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    5. Laden F, Bertrand KA, Altshul L, Aster JC, Korrick SA, Sagiv SK. Plasma organochlorine levels and risk of non-Hodgkin lymphoma in the Nurses' Health Study. Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5):1381-4.
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    6. Sagiv SK, Thurston SW, Bellinger DC, Tolbert PE, Altshul LM, Korrick SA. Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children. Am J Epidemiol. 2010 Mar 1; 171(5):593-601.
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    7. Mordukhovich I, Rossner P, Terry MB, Santella R, Zhang YJ, Hibshoosh H, Memeo L, Mansukhani M, Long CM, Garbowski G, Agrawal M, Gaudet MM, Steck SE, Sagiv SK, Eng SM, Teitelbaum SL, Neugut AI, Conway-Dorsey K, Gammon MD. Associations between polycyclic aromatic hydrocarbon-related exposures and p53 mutations in breast tumors. Environ Health Perspect. 2010 Apr; 118(4):511-8.
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    8. Bradshaw PT, Sagiv SK, Kabat GC, Satia JA, Britton JA, Teitelbaum SL, Neugut AI, Gammon MD. Consumption of sweet foods and breast cancer risk: a case-control study of women on Long Island, New York. Cancer Causes Control. 2009 Oct; 20(8):1509-15.
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    9. Sagiv SK, Gaudet MM, Eng SM, Abrahamson PE, Shantakumar S, Teitelbaum SL, Bell P, Thomas JA, Neugut AI, Santella RM, Gammon MD. Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer. Environ Res. 2009 Apr; 109(3):287-91.
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    10. McCarty KM, Santella RM, Steck SE, Cleveland RJ, Ahn J, Ambrosone CB, North K, Sagiv SK, Eng SM, Teitelbaum SL, Neugut AI, Gammon MD. PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer risk. Environ Health Perspect. 2009 Apr; 117(4):552-8.
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    11. Sagiv SK, Nugent JK, Brazelton TB, Choi AL, Tolbert PE, Altshul LM, Korrick SA. Prenatal organochlorine exposure and measures of behavior in infancy using the Neonatal Behavioral Assessment Scale (NBAS). Environ Health Perspect. 2008 May; 116(5):666-73.
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    12. Korrick SA, Sagiv SK. Polychlorinated biphenyls, organochlorine pesticides and neurodevelopment. Curr Opin Pediatr. 2008 Apr; 20(2):198-204.
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    13. Crew KD, Gammon MD, Terry MB, Zhang FF, Agrawal M, Eng SM, Sagiv SK, Teitelbaum SL, Neugut AI, Santella RM. Genetic polymorphisms in the apoptosis-associated genes FAS and FASL and breast cancer risk. Carcinogenesis. 2007 Dec; 28(12):2548-51.
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    14. Crew KD, Gammon MD, Terry MB, Zhang FF, Zablotska LB, Agrawal M, Shen J, Long CM, Eng SM, Sagiv SK, Teitelbaum SL, Neugut AI, Santella RM. Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2033-41.
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    15. Gaudet MM, Gammon MD, Bensen JT, Sagiv SK, Shantakumar S, Teitelbaum SL, Eng SM, Neugut AI, Santella RM. Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New York. Breast Cancer Res Treat. 2008 Mar; 108(1):93-9.
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    16. Sagiv SK, Gaudet MM, Eng SM, Abrahamson PE, Shantakumar S, Teitelbaum SL, Britton JA, Bell P, Thomas JA, Neugut AI, Santella RM, Gammon MD. Active and passive cigarette smoke and breast cancer survival. Ann Epidemiol. 2007 May; 17(5):385-93.
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    17. Sagiv SK, Tolbert PE, Altshul LM, Korrick SA. Organochlorine exposures during pregnancy and infant size at birth. Epidemiology. 2007 Jan; 18(1):120-9.
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    18. Shen J, Beth Terry M, Gammon MD, Gaudet MM, Teitelbaum SL, Eng SM, Sagiv SK, Neugut AI, Santella RM. IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer risk. Breast Cancer Res Treat. 2006 Sep; 99(1):1-7.
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    19. Rossner P, Terry MB, Gammon MD, Zhang FF, Teitelbaum SL, Eng SM, Sagiv SK, Gaudet MM, Neugut AI, Santella RM. OGG1 polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Apr; 15(4):811-5.
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    20. Shantakumar S, Gammon MD, Eng SM, Sagiv SK, Gaudet MM, Teitelbaum SL, Britton JA, Terry MB, Paykin A, Young TL, Wang LW, Wang Q, Stellman SD, Beyea J, Hatch M, Camann D, Prokopczyk B, Kabat GC, Levin B, Neugut AI, Santella RM. Residential environmental exposures and other characteristics associated with detectable PAH-DNA adducts in peripheral mononuclear cells in a population-based sample of adult females. J Expo Anal Environ Epidemiol. 2005 Nov; 15(6):482-90.
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    21. Shen J, Terry MB, Gammon MD, Gaudet MM, Teitelbaum SL, Eng SM, Sagiv SK, Neugut AI, Santella RM. MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer risk. Carcinogenesis. 2005 Dec; 26(12):2131-7.
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    22. Sagiv SK, Mendola P, Loomis D, Herring AH, Neas LM, Savitz DA, Poole C. A time-series analysis of air pollution and preterm birth in Pennsylvania, 1997-2001. Environ Health Perspect. 2005 May; 113(5):602-6.
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    23. Shen J, Gammon MD, Terry MB, Wang L, Wang Q, Zhang F, Teitelbaum SL, Eng SM, Sagiv SK, Gaudet MM, Neugut AI, Santella RM. Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2005 Feb; 14(2):336-42.
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    24. Terry MB, Gammon MD, Zhang FF, Eng SM, Sagiv SK, Paykin AB, Wang Q, Hayes S, Teitelbaum SL, Neugut AI, Santella RM. Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2004 Dec; 13(12):2053-8.
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    25. Gammon MD, Sagiv SK, Eng SM, Shantakumar S, Gaudet MM, Teitelbaum SL, Britton JA, Terry MB, Wang LW, Wang Q, Stellman SD, Beyea J, Hatch M, Kabat GC, Wolff MS, Levin B, Neugut AI, Santella RM. Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis. Arch Environ Health. 2004 Dec; 59(12):640-9.
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